CRISPR Products for Genome Editing
This portfolio has more than 55 patents in the US covering the use of CRISPR/Cas9 gene editing in all cells, including eukaryotic. Companies based in the US, using CRISPR/Cas9 will require a CVC license.
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Introduction to CRISPR
CRISPR Knowledge Base -
CRISPR-Methods and Tools
CRISPR Knowledge Base -
CRISPR-gRNA Design
CRISPR Knowledge Base -
CRISPR for Gene Activation and Repression
CRISPR Knowledge Base
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CRISPR Experiment Design Tool
CRISPR Tools -
CRISPR Knockout Manual
CRISPR Guides/Manuals -
CRISPR Case Studies
CRISPR Guides/Manuals -
CRISPR KO Results
Our data speaks for itself
Top Publications
Inferring and pertubing cell fate regulomes in human brain organoids.
Fleck, JS et al.
Nature. (2022)
doi: 10.1038/s41586-022-05279-8.
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Kang, Y. J. et al.
Nature Communications. (2015)
doi: 10.1038/ncomms9371
Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses.
Yamane, D. et al.
Nature Microbiology. (2019)
doi: 10.1038/s41564-019-0425-6
Testimonials
We are quite happy with the knockout cells that you made. This was a tricky knockout and hemizygous removal was much more prevalent than the double knockout, but you did it. In addition to your excellent genomic sequence characterization of both mutant LIF alleles, I have confirmed in our lab that the tumor cells have lost all mouse LIF production.
Dr. Robert Jackman
Boston University
Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service
Construct works beautifully, definitely will get more if needed.
Emily Chen
UCLA
CRISPR Lentivectors
The All-in-One Lentivectors worked very well.
Dr. Makoto Miyazaki
University of Colorado-Denver
CRISPR