CRISPR Genome Editing
Search CRISPR Gene Knockout Library
We offer genome-wide libraries of gene knockout sgRNAs for human, mouse, and rat genes in a full complement of viral and non-viral delivery systems, or ready-to-use CRISPR KO cell lines.
CRISPR Custom Services
Methylation & Base Editors
Inferring and pertubing cell fate regulomes in human brain organoids.
Fleck, JS et al.
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Kang, Y. J. et al.
Nature Communications. (2015)
We are quite happy with the knockout cells that you made. This was a tricky knockout and hemizygous removal was much more prevalent than the double knockout, but you did it. In addition to your excellent genomic sequence characterization of both mutant LIF alleles, I have confirmed in our lab that the tumor cells have lost all mouse LIF production.
Dr. Robert Jackman
Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service
Construct works beautifully, definitely will get more if needed.
The All-in-One Lentivectors worked very well.
Dr. Makoto Miyazaki
University of Colorado-Denver