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CRISPR Genome Editing

Edit, tag, silence, or activate any part of the genome with unprecedented specificity with our wide range of CRISPR products and services. Empower yourself with CRISPR today and make the genome your playground! abm has everything you need for all steps of your CRISPR experiment, from sgRNA design and cloning to screening and validation. Our expert scientists can also perform the entire CRISPR knockout experiment for you - just email us with your project details and we'll do the rest!
"We are very happy with the product and the turn around time, and would therefore order another reagent."

Dr. Alexandra Duverger, University of Alabama at Birmingham, CRISPR

Search CRISPR Gene Knockout Library

CRISPR Library
We offer genome-wide libraries of gene knockout sgRNAs for human, mouse, and rat genes in a full complement of viral and non-viral delivery systems, or ready-to-use CRISPR KO cell lines.


  • Introduction to CRISPR
    Introduction to CRISPR
    CRISPR Knowledge Base
  • CRISPR Methods and Tools
    CRISPR-Methods and Tools
    CRISPR Knowledge Base
  • sgRNA Design
    CRISPR-gRNA Design
    CRISPR Knowledge Base
  • CRISPR Gene Activation Repression
    CRISPR for Gene Activation and Repression
    CRISPR Knowledge Base
  • CRISPR Experimental Design Tool
    CRISPR Experiment Design Tool
    CRISPR Tools
  • CRISPR Knockout Manual
    CRISPR Knockout Manual
    CRISPR Guides/Manuals
  • CRISPR Case Studies
    CRISPR Case Studies
    CRISPR Guides/Manuals
  • CRISPR KO Results
    CRISPR KO Results
    Our data speaks for itself

Top Publications

Tumour-derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour-bearing mice.

Kandarian SC., et al.
J Cachexia Sarcopenia Muscle. (2018)

doi: 10.1002/jcsm.12346.

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.

Kang, Y. J. et al.
Nat. Commun. (2015)

doi: 10.1038/ncomms9371

Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis.

Jiang, G. et al.
Cancer Prev Res. (2016)

doi: 10.1158/1940-6207.CAPR-15-0338


We are quite happy with the knockout cells that you made. This was a tricky knockout and hemizygous removal was much more prevalent than the double knockout, but you did it. In addition to your excellent genomic sequence characterization of both mutant LIF alleles, I have confirmed in our lab that the tumor cells have lost all mouse LIF production.

Dr. Robert Jackman
Boston University

Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service

Construct works beautifully, definitely will get more if needed.

Emily Chen

CRISPR Lentivectors

The All-in-One Lentivectors worked very well.

Dr. Makoto Miyazaki
University of Colorado-Denver


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