CRISPR Genome Editing Services
Edit, tag, silence, or activate any part of the genome with unprecedented specificity with our CRISPR toolkit. Empower yourself with CRISPR today and make the genome your playground! abm has everything you need for all steps of your CRISPR experiment, from sgRNA design to screening and validation. Or, if you'd prefer, our expert scientists can perform the entire CRISPR knockout procedure for you.
"We are very happy with the product and the turn around time, and would therefore order another reagent."
Dr. Alexandra Duverger, University of Alabama at Birmingham, CRISPR
Dr. Alexandra Duverger, University of Alabama at Birmingham, CRISPR
Services
CRISPR Cell Services
CRISPR Custom Vector/Virus Services
More Hands-off CRISPR Services
Search Library
CRISPR Library
We offer genome-wide libraries of sgRNAs for human, mouse, and rat genes in a full complement of viral and non-viral delivery systems, or ready-to-use CRISPR KO cell lines.
Products
CRISPR Gene Editing Tools
CRISPR Libraries
GeneCraft-R Kits
Resources
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Introduction to CRISPR
CRISPR Knowledge Base -
CRISPR-Methods and Tools
CRISPR Knowledge Base -
CRISPR-gRNA Design
CRISPR Knowledge Base -
CRISPR for Gene Activation and Repression
CRISPR Knowledge Base
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CRISPR Experiment Design Tool
CRISPR Tools -
CRISPR Knockout Manual
CRISPR Guides/Manuals -
CRISPR Case Studies
CRISPR Guides/Manuals -
CRISPR KO Results
Product Data
Top Publications
Tumour-derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour-bearing mice.
Kandarian SC., et al.
J Cachexia Sarcopenia Muscle. (2018)
doi: 10.1002/jcsm.12346.
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Kang, Y. J. et al.
Nat. Commun. (2015)
doi: 10.1038/ncomms9371
Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis.
Jiang, G. et al.
Cancer Prev Res. (2016)
doi: 10.1158/1940-6207.CAPR-15-0338
Testimonials
We are quite happy with the knockout cells that you made. This was a tricky knockout and hemizygous removal was much more prevalent than the double knockout, but you did it. In addition to your excellent genomic sequence characterization of both mutant LIF alleles, I have confirmed in our lab that the tumor cells have lost all mouse LIF production.
Dr. Robert Jackman
Boston University
Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service
Construct works beautifully, definitely will get more if needed.
Emily Chen
UCLA
CRISPR Lentivectors
The All-in-One Lentivectors worked very well.
Dr. Makoto Miyazaki
University of Colorado-Denver
CRISPR