Anti-ATF2 (Phospho-Thr51(Thr69)) Antibody
Cat. No.
Y011030
Unit
100 μg
Price
$319.00
| Cat. No. | Y011030 |
| Name | Anti-ATF2 (Phospho-Thr51(Thr69)) Antibody |
| Clone | N/A |
| Category | Polyclonal Antibodies |
| Gene Name | ATF2 |
| Alias | TREB7, CRE-BP1, HB16 |
| Application | IHC |
| Application Info | IHC: 1:50~1:100 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014] |
| Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T). |
| Concentration | 1ug/ul |
| Recommended Dilutions | IHC: 1:50~1:100 |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | ATF-2 (hosphor-Thr69 or 51) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 69 or 51. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. |
| Guarantee | abm guarantees that all our Anti-ATF2 (Phospho-Thr51(Thr69)) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y011030 |
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