Anti-BAD (Phospho-Ser112) Antibody
Cat. No.
Y011067
Unit
100 μg
Price
$319.00
| Cat. No. | Y011067 |
| Name | Anti-BAD (Phospho-Ser112) Antibody |
| Clone | N/A |
| Category | Polyclonal Antibodies |
| Gene Name | BAD |
| Alias | BCL2L8, BBC2 |
| Application | WB,IHC |
| Application Info | WB: 1:500~1:1000 IHC: 1:50~1:100 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008] |
| Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human BAD around the phosphorylation site of serine 112 (H-S-SP-Y-P). |
| Concentration | 1ug/ul |
| Recommended Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | BAD (phospho-Ser112) antibody detects endogenous levels of BAD only when phosphorylated at serine 112. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site. |
| Guarantee | abm guarantees that all our Anti-BAD (Phospho-Ser112) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y011067 |
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