Anti-Glucagon Receptor Antibody
Cat. No.
Y030162
Unit
100ul
Price
$232.00
| Cat. No. | Y030162 |
| Name | Anti-Glucagon Receptor Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | Glucagon Receptor |
| Application | WB,ELISA,IP |
| Application Info | Western Blotting (starting dilution 1:200, dilution range 1:100-1:1000), immunoprecipitation [1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)], immunofluorescence (starting dilution 1:50, dilution range 1:50-1:500) and solid phase ELISA (starting dilution 1:30, dilution range 1:30-1:3000). |
| Raised In | Goat |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes. |
| Immunogen | Recombinant human Glucagon Receptor protein |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Western Blotting (starting dilution 1:200, dilution range 1:100-1:1000), immunoprecipitation [1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)], immunofluorescence (starting dilution 1:50, dilution range 1:50-1:500) and solid phase ELISA (starting dilution 1:30, dilution range 1:30-1:3000). |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition | Store at -20°C/1 year |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | Epitope mapping within an extracellular domain of the human Glucagon Receptor |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-Glucagon Receptor Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y030162 |
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