Anti-HDAC8 (Phospho-Ser39) Antibody
Cat. No.
Y011128
Unit
100 μg
Price
$319.00
| Cat. No. | Y011128 |
| Name | Anti-HDAC8 (Phospho-Ser39) Antibody |
| Clone | N/A |
| Category | Polyclonal Antibodies |
| Gene Name | HDAC8 |
| Alias | RPD3 |
| Application | IHC |
| Application Info | IHC: 1:50~1:100 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
| Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human HDAC8 around the phosphorylation site of serine 39 (R-A-SP-M-V). |
| Concentration | 1ug/ul |
| Recommended Dilutions | IHC: 1:50~1:100 |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | HDAC8 (phospho-Ser39) antibody detects endogenous levels of HDAC8 only when phosphorylated at serine 39. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site. |
| Guarantee | abm guarantees that all our Anti-HDAC8 (Phospho-Ser39) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y011128 |
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