Anti Human DUSP6 Polyclonal Antibody
Cat. No. | Y054549 |
Name | Anti Human DUSP6 Polyclonal Antibody |
Clone | Polyclonal |
Category | Polyclonal Antibodies |
Gene Name | DUSP6 |
Alias | MKP-3, PYST1 |
Application | WB,ELISA |
Application Info | ELISA 1:1,000~100,000 Western blotting 1:100~1,000 |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse |
Description | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014] |
Immunogen | Recombinant Protein |
Isotype | IgG |
Concentration | 1ug/ul |
Recommended Dilutions | ELISA 1:1,000~100,000 Western blotting 1:100~1,000 |
Storage Buffer | PBS, pH 7.4 with 0.1% sodium azide, 50% Glycerol |
Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse |
Purity | Antigen Affinity Purified |
Guarantee | abm guarantees that all our Anti Human DUSP6 Polyclonal Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y054549 |
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