Anti-PAK1/PAK2/PAK3 (Phospho-Thr423/Thr402/Thr421) Antibody
Cat. No.
Y011165
Unit
100 μg
Price
$319.00
| Cat. No. | Y011165 |
| Name | Anti-PAK1/PAK2/PAK3 (Phospho-Thr423/Thr402/Thr421) Antibody |
| Clone | N/A |
| Category | Polyclonal Antibodies |
| Gene Name | PAK1 |
| Application | IHC |
| Application Info | IHC: 1:50-1:100 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
| Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human PAK1 around the phosphorylation site of threonine 423 (R-S-TP-M-V). |
| Concentration | 1ug/ul |
| Recommended Dilutions | IHC: 1:50-1:100 |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | PAK1/PAK2/PAK3 (Phospho-Thr423/Thr402/Thr421) antibody detects endogenous levels of PAK1/PAK2/PAK3 only when phosphorylated at threonine 423/402/421. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. |
| Guarantee | abm guarantees that all our Anti-PAK1/PAK2/PAK3 (Phospho-Thr423/Thr402/Thr421) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y011165 |
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