Anti-TYK2 (Ab-1054) Antibody
Cat. No.
Y021118
Unit
100 μg
Price
$319.00
| Cat. No. | Y021118 |
| Name | Anti-TYK2 (Ab-1054) Antibody |
| Clone | N/A |
| Category | Polyclonal Antibodies |
| Gene Name | TYK2 |
| Alias | JTK1 |
| Application | IHC |
| Application Info | IHC: 1:50~1:100 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008] |
| Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human TYK2 around the phosphorylation site of tyrosine 1054 (H-E-YP-Y-R). |
| Concentration | 1ug/ul |
| Recommended Dilutions | IHC: 1:50~1:100 |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | TYK2 (Ab-1054) antibody detects endogenous levels of TYK2 protein around tyrosine 1054. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Caution | Not for diagnostic use. |
| Guarantee | abm guarantees that all our Anti-TYK2 (Ab-1054) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y021118 |
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