miRNA All-In-One cDNA Synthesis Kit
Cat. No.
G898
Unit
20 rxn
Price
$185.00
| Cat. No. | G898 | ||||||||
| Name | miRNA All-In-One cDNA Synthesis Kit | ||||||||
| Unit | 20 rxn | ||||||||
| Category | Reverse Transcriptase & RT-PCR | ||||||||
| Description |
The miRNA All-In-One cDNA Synthesis Kit provides a comprehensive solution for efficient synthesis of first-strand miRNA cDNA from RNA samples. The kit includes all necessary components for a hassle-free setup, enabling RNA molecules to undergo polyadenylation and reverse transcription in a simple, single-tube reaction. This process uses Poly(A) Polymerase, OneScript® Plus Reverse Transcriptase, and a modified Oligo d(T) with Adapter that anneals to poly(A)-tailed miRNA. The included SuperMix contains RNaseOFF Ribonuclease Inhibitor to protect RNA from degradation.
The synthesized first-strand miRNA cDNA can be directly used as a template for qPCR-based miRNA expression analysis with BlasTaq™ qPCR MasterMix (sold separately, Cat. No. G891). Users can choose from abm’s extensive collection of miRNA qPCR primers, covering all known miRNA sequences. Each primer set includes a unique miRNA Forward Primer and a Universal 3' miRNA Reverse Primer that binds to the complementary Adapter sequence on the modified Oligo d(T).
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| Storage Condition |
Store at -20°C. This product is stable for 2 years from the date of shipping if stored and handled properly. |
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| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. G898 |
Datasheet
| Can I use your miRNA cDNA synthesis kit for quantifying mature miRNAs with qPCR? | |
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Yes, the miRNA All-In-One cDNA Synthesis Kit is designed for synthesizing cDNA from miRNAs, which can be directly used for qPCR-based analysis. Pair with BlasTaq™ qPCR MasterMix (sold separately, Cat. No. G891) and the appropriate miRNA forward primer from our miRNA qPCR Primer Library.
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| What RNA samples are suitable for use with the miRNA cDNA Synthesis Kit? | |
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Both small RNA (200 ng) and total RNA (up to 2 μg) can be used. Small RNA typically yields better results, but both types are compatible with the kit.
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| How do I protect RNA integrity during the cDNA synthesis process? | |
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The kit includes RNaseOFF Ribonuclease Inhibitor, which protects RNA from degradation during the cDNA synthesis process.
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| What is the role of the modified Oligo d(T) with Adapter in the cDNA synthesis process? | |
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The modified Oligo d(T) with Adapter binds initiates polyA-tailing and reverse transcription of the mature miRNAs enabling the synthesis of cDNA for subsequent analysis. The adapter contains the Universal reverse sequence enabling easy quantification through real-time PCR.
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| Can I use my own primers for qPCR with this kit? | |
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The kit is optimized for use with our miRNA primers, but other primers compatible with the Universal 3' miRNA Reverse Primer may also work. For optimal results, we recommend using our forward miRNA primers found in the miRNA qPCR Primer Library.
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| Are custom miRNA primers available for miRNAs not listed on your website? | |
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Yes, we offer custom primer design services for miRNAs not currently available in our catalog. Contact technical@abmgood.com with the miRNA accession numbers, and we'll be happy to design the primers for you. |
| How should I store the synthesized cDNA for long-term use? | |
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The synthesized miRNA cDNA can be stored at -20°C for long-term use without compromising its quality.
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| Do you provide housekeeping gene primers for use as internal controls in miRNA qPCR? | |
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Yes, we offer various housekeeping gene primers, including U6 (Cat. No. MPH00001), SNORD44 (Cat. No. MPH00003), and SNORD48 (Cat. No. MPH00005), which can be used as internal controls in qPCR.
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| What is the miRBase Sequence Database, and how can it help with miRNA research? | |
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miRBase is a comprehensive database of predicted and validated miRNA sequences, providing unique identifiers for miRNAs and searchable information about miRNA sequences and their target genes.
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| Do you offer in situ miRNA detection methods or mutant constructs for miRNA-mRNA interaction studies? | |
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We do not offer in situ miRNA detection methods or pre-made mutant constructs, but we can create custom mutant constructs for 3'UTR miRNA reporter vectors. Contact techinical@abmgood.com for custom services.
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| What can I use the synthesized cDNA for? | |
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The high-quality cDNA can be used in a variety of downstream applications, including gene expression analysis, cloning, and PCR-based assays. BlasTaq™ 2X qPCR Master Mix (Cat. No. G891) is well suited to downstream qPCR applications.
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| How should I store the synthesized cDNA? | |
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Store the synthesized first-strand cDNA at -20°C for long-term use.
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| Why am I getting low cDNA yields? | |
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Low cDNA yields can be caused by poor RNA integrity, contamination, or insufficient RNA input. To improve yield:
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| How much RNA template should I use for cDNA synthesis? | |
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We recommend using 1 ng to 2 μg of RNA per reaction.
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Akaray, I., Ozal, S. A., Sancar, H., Ozal, E., & Ayaz, L. (2024). miR-124, miR-126-3p, and miR-200b: Potential therapeutic targets for VEGF-mediated complications in proliferative diabetic retinopathy. Indian Journal of Ophthalmology, 10-4103. https://doi.org/10.4103/ijo.ijo_1791_24
Akgün, A. E., Yaylalı, Y. T., Seçme, M., Dodurga, Y., & Şenol, H. (2022). Kynurenine–PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension. Anatolian journal of cardiology, 26(5), 388. https://doi.org/10.5152/AnatolJCardiol.2021.861
Al-Serwi, R. H., Othman, G., Dawood, A. F., Alhumaidan, A. K., Alharbi, H. S., El-Sherbiny, M., ... & Elsherbini, D. M. A. (2023). Impact of glycogen synthase kinase-3ß inhibition on rats' temporomandibular joint collagen-induced rheumatoid arthritis with correlation to miRNA-155/miRNA-24 expression. European Review for Medical & Pharmacological Sciences, 27(16). https://doi.org/10.26355/eurrev_202308_33393
Alacam, H., Akgun, S., Akca, H., Ozturk, O., Kabukcu, B. B., & Herken, H. (2016). miR-181b-5p, miR-195-5p and miR-301a-3p are related with treatment resistance in schizophrenia. Psychiatry research, 245, 200-206. https://doi.org/10.1016/j.psychres.2016.08.037
Arslan, G. K. (2023). Pandemik SARS-COV-2 enfeksiyonu geçiren hastalarda mirna araştırılması. https://hdl.handle.net/20.500.12452/10307
Aziret, M., Eskiler, G. G., Çakar, G. Ç., Özkan, A. D., Ercan, M., Bilir, C., ... & Duman, M. (2023). Effect of the MiR-99b and MiR-135b on peritoneal carcinomatosis and liver metastasis in colorectal cancer. Clinics, 78, 100271. https://doi.org/10.1016/j.clinsp.2023.100271
Bahtiyar, N., Onaran, İ., Aydemir, B., Baykara, O., Toplan, S., Agaoglu, F. Y., & Akyolcu, M. C. (2018). Monitoring of platelet function parameters and microRNA expression levels in patients with prostate cancer treated with volumetric modulated arc radiotherapy. Oncology Letters, 16(4), 4745-4753. https://doi.org/10.3892/ol.2018.9167
Bai, Y., Pan, B., Zhan, X., Silver, H., & Li, J. (2021). MicroRNA 195-5p targets Foxo3 promoter region to regulate its expression in granulosa cells. International Journal of Molecular Sciences, 22(13), 6721. https://doi.org/10.3390/ijms22136721
Baltaci, S. B., Unal, O., Gulbahce-Mutlu, E., Gumus, H., Pehlivanoglu, S., Yardimci, A., ... & Baltaci, A. K. (2022). The role of zinc status on spatial memory, hippocampal synaptic plasticity, and insulin signaling in icv-STZ-induced sporadic Alzheimer’s-like disease in rats. Biological Trace Element Research, 1-11. https://doi.org/10.1007/s12011-021-02999-2
Becker, W., Nagarkatti, M., & Nagarkatti, P. S. (2018). miR-466a targeting of TGF-β2 contributes to FoxP3+ regulatory T cell differentiation in a murine model of allogeneic transplantation. Frontiers in immunology, 9, 688. https://doi.org/10.3389/fimmu.2018.00688
Cabus, U., Secme, M., Kabukcu, C., Cil, N., Dodurga, Y., Mete, G., & Fenkci, I. V. (2021). Boric acid as a promising agent in the treatment of ovarian cancer: Molecular mechanisms. Gene, 796, 145799. https://doi.org/10.1016/j.gene.2021.145799
Çağıl, F. Z., Ak, K., Rafiqi, A. M., Saraçoğlu, A., Öter, G. N., & Tetik, Ş. (2024). Determination of Early Diagnostic Biomarkers of Renal Dysfunction After Cardiopulmonary Bypass: miR-21 and miR10a Mediated Postoperative Inflammation. Clinical and Experimental Health Sciences, 14(1), 245-252. https://doi.org/10.33808/clinexphealthsci.1222499
Chen, G., Teng, Z., Zhu, Z., & Li, X. (2022). miR‐145‐3p Hampers the Malignant Progression of Esophageal Carcinoma via CXCL5 Downregulation. Analytical Cellular Pathology, 2022(1), 5418356. https://doi.org/10.1155/2022/5418356
Chen, W., Jiang, J., Gong, L., Shu, Z., Xiang, D., Zhang, X., ... & Diao, H. (2021). Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis. Journal of Experimental & Clinical Cancer Research, 40, 1-18. https://doi.org/10.1186/s13046-020-01803-8
Chen, X., Zhang, Q., Ma, W., Lan, T., Hong, Z., & Yuan, Y. (2018). The Abnormal Expression of MicroRNA‐542‐3p in Hepatocellular Carcinoma and Its Clinical Significance. Disease Markers, 2018(1), 3973250. https://doi.org/10.1155/2018/3973250
Chen, Y., Zhang, X., Jiang, J., Luo, M., Tu, H., Xu, C., ... & Guo, X. (2023). Regulation of Miwi-mediated mRNA stabilization by Ck137956/Tssa is essential for male fertility. BMC biology, 21(1), 89. https://doi.org/10.1186/s12915-023-01589-z
Cheng, Y., Wang, L., Abbas, M., Huang, X., Wang, Q., Wu, A., ... & Li, Q. (2021). MicroRNA319-mediated gene regulatory network impacts leaf development and morphogenesis in poplar. Forestry Research, 1(1), 1-10. https://doi.org/10.48130/FR-2021-0004
Cheng, Y., Wang, Q., Yang, L., Li, Q., & Yan, X. (2024). MiR319a-mediated salt stress response in poplar. Horticulture Research, uhae157. https://doi.org/10.1093/hr/uhae157
Cui, Y., Zheng, H., Zhou, Z., Liu, S., Shen, M., Qiu, R., ... & Fan, H. (2025). Identification of a ceRNA Network Regulating Malignant Transformation of Isocitrate Dehydrogenase Mutant Astrocytoma: An Integrated Bioinformatics Study. Current Computer-Aided Drug Design. https://doi.org/10.2174/0115734099293010240810181446
Dawood, A. F., Younes, S., Alzamil, N. M., Alradini, F. A., & Saja, M. F. (2022). Inhibition of glycogen synthase kinase-3β protects against collagen type II-induced arthritis associated with the inhibition of miR155/24 and inflammation and upregulation of apoptosis in rats. Archives of Physiology and Biochemistry, 128(3), 679-687. https://doi.org/10.1080/13813455.2020.1716021
Demiray, A. G., Demiray, A., Yaren, A., Taşköylü, B. Y., Doğu, G. G., Değirmencioğlu, S., ... & Özdemir, M. (2022). Evaluation of Serum microRNA Let-7c and Let-7d as Predictive Biomarkers for Metastatic Pancreatic Cancer. The Turkish Journal of Gastroenterology, 33(8), 696. https://doi.org/10.5152/tjg.2022.21829
Demiray, A., Sarı, T., Çalışkan, A., Nar, R., Aksoy, L., & Akbubak, İ. H. (2021). Serum microRNA signature is capable of predictive and prognostic factor for SARS-COV-2 virulence. Turkish Journal of Biochemistry, 46(3), 245-253. https://doi.org/10.1515/tjb-2020-0520
Doğanlar, O., Doğanlar, Z. B., Chasan, T., & Kurtdere, A. K. (2021). Prolonged sub-lethal exposure to galaxolide (HHCB) and tonalide (AHTN) promotes the metastatic potential of glioblastoma tumor spheroids. Neurotoxicology, 87, 219-230. https://doi.org/10.1016/j.neuro.2021.10.006
Gelisin, O., Susgun, S., Toruntay, C., Yabaci, A., Baran, G., Gursoy, A. E. B., ... & Yucesan, E. (2023). Evaluation of miR-526b-3p, miR-1179, miR-3529-3p, miR-5011-5p as potential diagnostic biomarkers in isolated cervical dystonia. Revue Neurologique, 179(6), 563-569. https://doi.org/10.1016/j.neurol.2022.10.008
Guo, X., Tian, T., Deng, X., Song, Y., Zhou, X., & Song, E. (2022). CRISPR/Cas13a assisted amplification of magnetic relaxation switching sensing for accurate detection of miRNA-21 in human serum. Analytica Chimica Acta, 1209, 339853. https://doi.org/10.1016/j.aca.2022.339853
Han, S., Wang, D., Tang, G., Yang, X., Jiao, C., Yang, R., ... & Li, X. (2017). Suppression of miR-16 promotes tumor growth and metastasis through reversely regulating YAP1 in human cholangiocarcinoma. Oncotarget, 8(34), 56635. https://doi.org/10.18632/oncotarget.17832
Hatiboglu, M. A., Karacam, B., Khan, I., Akdur, K., Elbasan, E. B., Mahfooz, S., ... & Oztanir, M. N. (2024). Liquid biopsy for CNS lymphoma: CSF exosomes and CSF exosomal miR-15a, miR-21, miR-155, miR-210, and miR-19b are promising biomarkers for diagnosis. Molecular Biology Reports, 51(1), 1035. https://doi.org/10.1007/s11033-024-09967-8
Hekim, N., Gunes, S., Ergun, S., Barhan, E. N., & Asci, R. (2024). Investigation of sperm hsa-mir-145-5p and MLH1 expressions, seminal oxidative stress and sperm DNA fragmentation in varicocele. Molecular Biology Reports, 51(1), 588. https://doi.org/10.1007/s11033-024-09534-1
Huang, Z., Zhang, Y., Zhou, J., & Zhang, Y. (2017). Urinary exosomal miR‐193a can be a potential biomarker for the diagnosis of primary focal segmental glomerulosclerosis in children. BioMed Research International, 2017(1), 7298160. https://doi.org/10.1155/2017/7298160
Jabbar, N. K., Almzaiel, A. J. T., & Jaber, F. A. (2019). The pro‐inflammatory role of microRNA‐29b in diabetic nephropathy. Asian J Pharm Clin Res, 12, 210-213. http://dx.doi.org/10.22159/ajpcr.2019.v12i10.34766
Jafarnejad, S. M., Ardekani, G. S., Ghaffari, M., Martinka, M., & Li, G. (2013). Sox4-mediated Dicer expression is critical for suppression of melanoma cell invasion. Oncogene, 32(17), 2131-2139. https://doi.org/10.1038/onc.2012.239
Jang, S., Lee, M. S., Kang, S. A., Kim, C. T., & Kim, Y. (2022). Portulaca oleracea L. Extract regulates hepatic cholesterol metabolism via the AMPK/MicroRNA-33/34a pathway in rats fed a high-cholesterol diet. Nutrients, 14(16), 3330. https://doi.org/10.3390/nu14163330
Ji, W., Zhang, W., Wang, X., Shi, Y., Yang, F., Xie, H., ... & Guan, X. (2020). c-myc regulates the sensitivity of breast cancer cells to palbociclib via c-myc/miR-29b-3p/CDK6 axis. Cell death & disease, 11(9), 760. https://doi.org/10.1038/s41419-020-02980-2
Jung, S., Lee, M. S., Chang, E., Kim, C. T., & Kim, Y. (2021). Mulberry (Morus alba L.) fruit extract ameliorates inflammation via regulating microRNA-21/132/143 expression and increases the skeletal muscle mitochondrial content and AMPK/SIRT activities. Antioxidants, 10(9), 1453. https://doi.org/10.3390/antiox10091453
Kaur, G., Pippin, J. A., Chang, S., Redmond, J., Chesi, A., Wells, A. D., ... & Wagley, Y. (2024). Osteoporosis GWAS-implicated DNM3 locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem/progenitor cells through oscillating miR-199a-5p levels. JBMR plus, 8(5), ziae051. https://doi.org/10.1093/jbmrpl/ziae051
Kaymaz, S., Aydın, D., Uğur, K., Çobankara, V., & Tan, S. (2023). Expression Levels and Clinical Values of miR-195, miR-424, miR-10b, miR-103a-3p, and miR-542-3p in Vasculo-Behçet’s Disease. Mediterranean Journal of Rheumatology, 35(2), 255. https://doi.org/10.31138/mjr.030623.elc
Kim, S., Lee, M. S., Jung, S., Son, H. Y., Park, S., Kang, B., ... & Kim, Y. (2018). Ginger extract ameliorates obesity and inflammation via regulating microRNA-21/132 expression and AMPK activation in white adipose tissue. Nutrients, 10(11), 1567. https://doi.org/10.3390/nu10111567
Lang, B., & Zhao, S. (2018). miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2. Oncology reports, 39(1), 71-80. https://doi.org/10.3892/or.2017.6064
Lee, E., Lee, M. S., Chang, E., Kim, C. T., Choi, A. J., Kim, I. H., & Kim, Y. (2021). High hydrostatic pressure extract of mulberry leaves ameliorates hypercholesterolemia via modulating hepatic microRNA-33 expression and AMPK activity in high cholesterol diet fed rats. Food & Nutrition Research, 65. https://doi.org/10.29219/fnr.v65.7587
Lee, M. S., & Kim, Y. (2021). Effects of mulberry fruit juice powder on inflammation and microRNA-132/143 regulation in 3T3-L1 adipocytes. Journal of Nutrition and Health, 54(5), 448-458. https://doi.org/10.4163/jnh.2021.54.5.448
Lee, M. S., Kim, C., Ko, H., & Kim, Y. (2022). 추출물의간 microRNA-221/222 발현및. J Nutr, 55(2), 227-239. https://doi.org/10.4163/jnh.2022.55.2.227
Lee, M. S., Lee, J., & Kim, Y. (2022). Green tea extract containing piper retrofractum fruit ameliorates DSS-induced colitis via modulating MicroRNA-21 expression and NF-κB activity. Nutrients, 14(13), 2684. https://doi.org/10.3390/nu14132684
Lee, S., Lee, M. S., Chang, E., Lee, Y., Lee, J., Kim, J., ... & Kim, Y. (2020). Mulberry fruit extract promotes serum HDL-cholesterol levels and suppresses hepatic microRNA-33 expression in rats fed high cholesterol/cholic acid diet. Nutrients, 12(5), 1499. https://doi.org/10.3390/nu12051499
Lei, L., Wang, Y., Liu, R., Feng, J., Tang, J., Gou, J., ... & Li, X. (2023). Transfer of miR‐4755‐5p through extracellular vesicles and particles induces decitabine resistance in recipient cells by targeting CDKN2B. Molecular Carcinogenesis, 62(6), 743-753. https://doi.org/10.1002/mc.23521
Li, B., Su, Y., Xiang, N., Qin, B., Li, G., Wan, T., ... & Feng, Q. S. (2021). Comparative serum microRNA array analysis of the spleen‐stomach dampness‐heat syndrome in different diseases: Chronic hepatitis B and chronic gastritis. The Anatomical Record, 304(11), 2620-2631. https://doi.org/10.1002/ar.24690
Li, D., Wang, Y., Jin, X., Hu, D., Xia, C., Xu, H., & Hu, J. (2020). NK cell-derived exosomes carry miR-207 and alleviate depression-like symptoms in mice. Journal of neuroinflammation, 17, 1-19. https://doi.org/10.1186/s12974-020-01787-4
Li, X., Zhang, D., Gan, X., Liu, P., Zheng, Q., Yang, T., ... & Yan, Y. (2021). A cascade signal amplification based on dynamic DNA nanodevices and CRISPR/Cas12a trans-cleavage for highly sensitive microRNA sensing. ACS Synthetic Biology, 10(6), 1481-1489. https://doi.org/10.1021/acssynbio.1c00064
Li, Y., Zhuang, Q., Tao, L., Zheng, K., Chen, S., Yang, Y., ... & Wang, Z. (2022). Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting ERK/NF‐κB pathway. Cell proliferation, 55(10), e13291. https://doi.org/10.1111/cpr.13291
Liu, P., Chen, B., Gu, Y., & Liu, Q. (2018). PNMA1, regulated by miR-33a-5p, promotes proliferation and EMT in hepatocellular carcinoma by activating the Wnt/β-catenin pathway. Biomedicine & Pharmacotherapy, 108, 492-499. https://doi.org/10.1016/j.biopha.2018.09.059
Majed, S. O. Mace-Seq-Based Total Rna Profiling in Breast Cancer: Tumor Suppressive Mir-1185-P5 Promotes Cell Migration and Invasion by Targeting Bcas1, Casc3, Gata2, and Vopp1. Casc3, Gata2, and Vopp1. https://dx.doi.org/10.2139/ssrn.4902587
Majeed, I., Yaqub, A., & Ayub, M. (2024). Growth Performance, Immune Modulation, and Gene Expression Enhancement in Labeo rohita Through Integrated Probiotic Bacillus licheniformis and Phytobiotic Cinnamomum verum Strategies. Aquaculture Research, 2024(1), 1575503. https://doi.org/10.1155/are/1575503
Manning, S., Torii, S., Atkins, H. M., & Kawasawa, Y. I. (2021). Dynamic expression of smRNA from fecal exosome in disease progression of an inflammatory bowel disorder mouse model. bioRxiv, 2021-02. https://doi.org/10.21037/exrna-21-8
Mawlah, Y., Naji, M., Imari, M., & Abdulabbas, H. (2022). Micro-RNA evaluation, specification, and stabilization study in mixed/non-mixed body fluids as a specific molecular marker. J Adv Biotechnol Exp Ther, 5(2), 347-357. https://doi.org/10.5455/jabet.2022.d120
Mumtaz, S., Usman Rashid, M., Khan, R. U., & Malkani, N. (2023). miR-4482 and miR-3912 aim for 3ʹUTR of ERG mRNA in prostate cancer. Plos one, 18(6), e0286996. https://doi.org/10.1371/journal.pone.0286996
Mutlu, D., Gunal, B., Secme, M., Bozbeyoglu, K. N. N., Abban, M. G., Mercan, D. N., ... & Arslan, S. (2024). Biological activities of Liquidambar orientalis: antibiofilm, cytotoxicity, apoptosis, and miRNA expressions. Botanica Serbica, 48(1), 17-26. https://doi.org/10.2298/BOTSERB2401017M
Ooki, A., Onodera, S., Saito, A., Oguchi, A., Murakawa, Y., Sakamoto, T., ... & Azuma, T. (2020). CAGE-seq analysis of osteoblast derived from cleidocranial dysplasia human induced pluripotent stem cells. Bone, 141, 115582. https://doi.org/10.1016/j.bone.2020.115582
Pervez, M. A., Khan, D. A., Gilani, S. T. A., Fatima, S., Ijaz, A., & Nida, S. (2022). Hepato-protective effects of delta-tocotrienol and alpha-tocopherol in patients with non-alcoholic fatty liver disease: regulation of circulating MicroRNA expression. International Journal of Molecular Sciences, 24(1), 79. https://doi.org/10.3390/ijms24010079
Qin, X., Chen, J., Wu, L., & Liu, Z. (2017). MiR-30b-5p acts as a tumor suppressor, repressing cell proliferation and cell cycle in human hepatocellular carcinoma. Biomedicine & Pharmacotherapy, 89, 742-750. https://doi.org/10.1016/j.biopha.2017.02.062
Qin, X., Li, C., Guo, T., Chen, J., Wang, H. T., Wang, Y. T., ... & Liu, Q. Y. (2017). Upregulation of DARS2 by HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5 pathway. Journal of Experimental & Clinical Cancer Research, 36, 1-16. https://doi.org/10.1186/s13046-017-0618-x
Seçme, M., Dodurga, Y., Demirkan, N. Ç., Kaçar, N., Günel, N. S., & Açıkbaş, İ. (2024). Determination of T-cell clonality and expression profiles of Toll-like receptors signaling pathway genes and related miRNAs in patients with mycosis fungoides. Gene, 891, 147825. https://doi.org/10.1016/j.gene.2023.147825
Secme, M., Mutlu, D., Elmas, L., & Arslan, S. (2023). Assessing effects of caffeic acid on cytotoxicity, apoptosis, invasion, GST enzyme activity, oxidant, antioxidant status and micro-RNA expressions in HCT116 colorectal cancer cells. South African Journal of Botany, 157, 19-26. https://doi.org/10.1016/j.sajb.2023.03.046
Shen, C., Huang, Y. Y., He, C. T., Zhou, Q., Chen, J. X., Tan, X., ... & Yang, Z. Y. (2017). Comparative analysis of cadmium responsive microRNAs in roots of two Ipomoea aquatica Forsk. cultivars with different cadmium accumulation capacities. Plant Physiology and Biochemistry, 111, 329-339. https://doi.org/10.1016/j.plaphy.2016.12.013
Shen, C., Huang, Y. Y., Xin, J. L., He, C. T., & Yang, Z. Y. (2022). A novel microRNA IamiR-4-3p from water spinach (Ipomoea aquatica Forsk.) increased Cd uptake and translocation in Arabidopsis thaliana. Environmental Science and Pollution Research, 29(27), 41375-41385. https://doi.org/10.1007/s11356-022-18875-y
Sundar, I. K., Li, D., & Rahman, I. (2019). Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers. Journal of extracellular vesicles, 8(1), 1684816. https://doi.org/10.1080/20013078.2019.1684816
Tang, W., Yan, H., Chen, X., Pu, Y., Qi, X., Dong, L., & Su, C. (2024). hUCMSC-derived extracellular vesicles relieve cisplatin-induced granulosa cell apoptosis in mice by transferring anti-apoptotic miRNAs. The Journal of Biomedical Research. https://doi.org/10.7555/jbr.37.20230310
Tastan Eroglu, Z., Ozkan Sen, D., & Oncu, E. (2024). Association of Peri-Implant Keratinized Mucosa Width and Mucosal Thickness with Early Bone Loss: A Cross-Sectional Study. Journal of Clinical Medicine, 13(7), 1936. https://doi.org/10.3390/jcm13071936
Tjandrawinata, R. R., & Nurkolis, F. (2024). A Comparative Analysis on Impact of Extraction Methods on Carotenoids Composition, Antioxidants, Antidiabetes, and Antiobesity Properties in Seagrass Enhalus acoroides: In Silico and In Vitro Study. Marine Drugs, 22(8), 365. https://doi.org/10.3390/md22080365
Tuncer, S. B., Akdeniz, D., Celik, B., Kilic, S., Sukruoglu, O., Avsar, M., ... & Yazici, H. (2019). The expression levels of miRNA-15a and miRNA-16-1 in circulating tumor cells of patients with diffuse large B-cell lymphoma. Molecular biology reports, 46, 975-980. https://doi.org/10.1007/s11033-018-4554-4
Wang, L., Wang, J., Wang, Z., Zhou, J., & Zhang, Y. (2021). Higher urine exosomal miR-193a is associated with a higher probability of primary focal segmental glomerulosclerosis and an increased risk of poor prognosis among children with nephrotic syndrome. Frontiers in Cell and Developmental Biology, 9, 727370. https://doi.org/10.3389/fcell.2021.727370
Wang, Y., Li, M., Chen, L., Bian, H., Chen, X., Zheng, H., ... & Xu, H. (2021). Natural killer cell-derived exosomal miR-1249-3p attenuates insulin resistance and inflammation in mouse models of type 2 diabetes. Signal Transduction and Targeted Therapy, 6(1), 409. https://doi.org/10.1038/s41392-021-00805-y
Wu, G., Ju, X., Wang, Y., Li, Z., & Gan, X. (2019). Up-regulation of SNHG6 activates SERPINH1 expression by competitive binding to miR-139-5p to promote hepatocellular carcinoma progression. Cell Cycle, 18(16), 1849-1867. https://doi.org/10.1080/15384101.2019.1629772
Wu, G., Ma, L., Wang, L., Zhou, J., Ma, Y., & Yang, C. (2020). Analysis of transcriptome and miRNAome in the muscle of bamei pigs at different developmental stages. Animals, 10(7), 1198. https://doi.org/10.3390/ani10071198
Wu, L., Chang, L., Wang, H., Ma, W., Peng, Q., & Yuan, Y. (2018). Clinical significance of C/D box small nucleolar RNA U76 as an oncogene and a prognostic biomarker in hepatocellular carcinoma. Clinics and Research in Hepatology and Gastroenterology, 42(1), 82-91. https://doi.org/10.1016/j.clinre.2017.04.018
Xiao, Y., Najeeb, R. M., Ma, D., Yang, K., Zhong, Q., & Liu, Q. (2019). Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms. Journal of Experimental & Clinical Cancer Research, 38, 1-13. https://doi.org/10.1186/s13046-019-1444-0
Xiong, X., Sun, D., Chai, H., Shan, W., Yu, Y., Pu, L., & Cheng, F. (2015). MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma. Biochemical and biophysical research communications, 465(2), 262-269. https://doi.org/10.1016/j.bbrc.2015.08.013
Yan, Y., Tian, L. Y., Jia, Q., Han, Y., Tian, Y., Chen, H. N., ... & Zhao, X. J. (2023). MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury. Cell Death Discovery, 9(1), 77. https://doi.org/10.1038/s41420-023-01372-7
Yaren, A., Gökdeniz Yıldırım, A., Demiray, A., Koç, A. C., & Şenol, H. (2023). Association between 20 serum mirnas and clinicopathological variables in patients with breast cancer. Pamukkale Tıp Dergisi. https://hdl.handle.net/11499/51434
Yea, J. H., Yoon, Y. M., Lee, J. H., Yun, C. W., & Lee, S. H. (2021). Exosomes isolated from melatonin-stimulated mesenchymal stem cells improve kidney function by regulating inflammation and fibrosis in a chronic kidney disease mouse model. Journal of Tissue Engineering, 12, 20417314211059624. https://doi.org/10.1177/20417314211059624
Yildirim, A. G., Demiray, A., Koc, A. C., Senol, H., & Yaren, A. (2023). Association between 20 serum mirnas and clinicopathological variables in patients with breast cancer/Meme kanserli hastalarda 20 serum mirna'nin klinikopatolojik degiskenler ile iliskisi. Pamukkale Medical Journal, 16(2), 168-179. https://doi.org/10.31362/patd.1216451
Yıldırım, O., Seçme, M., Dodurga, Y., Mete, G. A., & Fenkci, S. M. (2024). Effects of boric acid on proliferation, apoptosis and miRNAs in medullary thyroid cancer cells. https://doi.org/10.21203/rs.3.rs-3986243/v1
Zapała, B., Kamińska, A., Piwowar, M., Paziewska, A., Gala-Błądzińska, A., & Stępień, E. Ł. (2023). miRNA signature of urine extracellular vesicles shows the involvement of inflammatory and apoptotic processes in diabetic chronic kidney disease. Pharmaceutical research, 40(4), 817-832. https://doi.org/10.1007/s11095-023-03481-5
Zeng, Q., Jin, F., Qian, H., Chen, H., Wang, Y., Zhang, D., ... & Chai, C. (2022). The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells. Carcinogenesis, 43(2), 150-159. https://doi.org/10.1093/carcin/bgab124
Zhang, X., Pan, B., Qiu, J., Ke, X., Shen, S., Wang, X., & Tang, N. (2022). lncRNA MIAT targets miR‐411‐5p/STAT3/PD‐L1 axis mediating hepatocellular carcinoma immune response. International Journal of Experimental Pathology, 103(3), 102-111. https://doi.org/10.1111/iep.12440
Zhang, Y., Yang, Y., Guo, J., Cui, L., Yang, L., Li, Y., ... & Song, X. (2022). miR‐146a enhances regulatory T‐cell differentiation and function in allergic rhinitis by targeting STAT5b. Allergy, 77(2), 550-558. https://doi.org/10.1111/all.15163
Zhou, Y., Mabrouk, I., Ma, J., Liu, Q., Song, Y., Xue, G., ... & Sun, Y. (2024). Chromosome-level genome sequencing and multi-omics of the Hungarian White Goose (Anser anser domesticus) reveals novel miRNA-mRNA regulation mechanism of waterfowl feather follicle development. Poultry Science, 103933. https://doi.org/10.1016/j.psj.2024.103933
이막순, & 김양하. (2022). 고콜레스테롤 식이 섭취 쥐에서 quercetin 의 간 AMPK 및 microRNA-21 조절을 통한 지질대사 개선 효과. Journal of Nutrition and Health, 55(1), 36-46. https://doi.org/10.4163/jnh.2022.55.1.36
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